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The innate immune system, which is also referred to as non-specific immune system is the secondary line of defence mechanism in living organisms. This comprises the protection of the host from infection through certain mechanisms, which means that the recognition and response by the cells of the innate system to pathogens in a generic way. When compared to the adaptive immune system, the immunity conferred to the host by it is not a permanent one. Innate immune systems provide immediate protection against infection, and are present in all living organisms.
The significant functions of the innate immune system in the vertebrates include, activating the adaptive immune system by a technique called, antigen presentation; recruitment of immune cells to the infected sites by producing specialized biochemical mediators, known as cytokines; identifying and removing foreign substances present in the body tissues, organs, and body fluids like blood and lymph, with the help of specialized leucocytes; being a physical barrier for example, the process of desquamation of the skin is a physical barrier to most pathogenic bacteria, and chemical barrier like lysozyme present in the saliva acts as a chemical barrier to infectious agents.
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